Products
PRODUCTS
CDMO Service
PanGen provides customers with services ranging from the establishment of high-performance recombinant CHO production cell lines to the development of production processes and analytical method development using PanGen CHO-TECHTM core technology and biopharmaceutical product development technology.
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Producer Cell Line Development
- Sales of producer cell lines already established (40 cell lines) by using PanGen’s platform patented technology
- Contract development of producer cell line with high productivity and expression stability by using PanGen’s platform patented technology within short period of time(approximately 5 months)
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Manufacturing Process Development
- Development and technology transfer of the manufacturing process in 5L bioreactor scale
(culture, purification and QC analysis methods) by implementing PanGen’s abundant experience and knowhow
- Development and technology transfer of the manufacturing process in 5L bioreactor scale
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Analytical method Development
- Provides analysis method development services for customized quality assessment of various customers.
- Provides protein equivalence comparison and protein structure and characteristic analysis services.
CHO cell line
High expression CHO cell lines that produce therapeutic proteins and therapeutic antibody proteins are being developed using PanGen’s patented technology, PanGen CHO-TECHTM. These high expression, high stability CHO cell lines are highly suitable for mass production of therapeutic proteins for commercialization.
Cytokines & Growth Factors
| Cat. # | Expressed Protein | Abbreviation |
|---|---|---|
| PGA101 | Human Erythropoietin | EPO |
| PGA102 | Human Granulocyte Colony Stimulating Factor | G-CSF |
| PGA103 | Human Granulocyte Macrophage Colony Stimulating Factor | GM-CSF |
| PGA104 | Human Hepatocyte Growth Factor | HGF |
| PGA106 | Human Interferon Beta | IFN-β |
| PGA109 | Human Interleukin-2 | IL-2 |
| PGA111 | Human Interleukin-4 | IL-4 |
| PGA112 | Human Interleukin-6 | IL-6 |
| PGA116 | Human Bone Morphogenetic Protein-4 | BMP-4 |
| PGA117 | Human Bone Morphogenetic Protein-7 | BMP-7 |
| PGA119 | Human Transforming Growth Factor Beta 3 | TGF-β3 |
| PGA120 | Human Vascular Endothelial Growth Factor 165 | VEGF165 |
| PGA132 | Human Darbepoetin Alfa | Darbepoetin alfa |
| PGA133 | Human Activin A | Activin A |
| PGA134 | Human Leukemia Inhibitory Factor | LIF |
| PGA135 | Human Glial-derived Neurotrophic Factor | GDNF |
| PGA136 | Human Neurotrophin-3 | NT3 |
| PGA137 | Noggin | Noggin |
Haemostasis, Thrombosis & Immunohaematology
| Cat. # | Expressed Protein | Abbreviation |
|---|---|---|
| PGB205 | Human Blood Coagulation Factor VIII | FVIII |
| PGB207 | Human Blood Coagulation Factor VII | FVII |
Hormones
| Cat. # | Expressed Protein | Abbreviation |
|---|---|---|
| PGC301 | Human Follicle Stimulating Hormone | FSH |
| PGC302 | Human Growth Hormone | hGH |
| PGC305 | Human Chorionic Gonadotropin | CG |
Enzymes & Others
| Cat. # | Expressed Protein | Abbreviation |
|---|---|---|
| PGD402 | Human α-Galactosidase | α-Gal |
| PGD403 | Human a-Glucosidase | GAA |
| PGD406 | alpha-L-iduronidase | IDUA |
| PGD407 | Idursulfase | IDS |
| PGD410 | Human β-glucocerebrosidase | GCR |
Recombinant Monoclonal antibodies
| Cat. # | Expressed Protein | Abbreviation |
|---|---|---|
| PGF602 | Rituximab | |
| PGF603 | Bevacizumab | |
| PGF604 | Etanercept | |
| PGF605 | Trastuzumab | |
| PGF606 | Infliximab | |
| PGF607 | Cetuximab | |
| PGF608 | Adalimumab | |
| PGF610 | Aflibercept | |
| PGF611 | Denosumab | |
| PGF612 | Pembrolizumab | |
| PGF614 | Romosozumab |